Analysis of Single-Cell RNA-seq Data with Python

Hands-on workshop series on single-cell RNA-seq analysis using Python and Scanpy.

Instructor: Yura Song, PhD and Zian Liu, PhD

Term: Spring

Location: Université Libre de Bruxelles, Brussels, Belgium

Overview

Workshop series organised as part of the Bioinformatics Forum at Université Libre de Bruxelles (ULB), introducing practical analysis workflows for single-cell RNA-seq data using Python.

The workshops are based on PBMC single-cell datasets and focus on reproducible analysis workflows using Scanpy and related Python tools.

Topics covered

  • Quality control and filtering
  • Normalisation and preprocessing
  • Dimensionality reduction
  • Clustering and annotation
  • Differential gene expression analysis
  • Gene regulatory network inference with SCENIC
  • Downstream biological interpretation

Course materials

Schedule

Week Date Topic Materials
1 Mar 2026 Introduction to single-cell RNA-seq analysis with Python

Hands-on introduction to Scanpy-based analysis of PBMC single-cell RNA-seq data, including quality control, preprocessing, dimensionality reduction and clustering.

2 Jun 2026 Downstream analysis of single-cell RNA-seq data

Follow-up workshop focusing on downstream analysis including differential gene expression analysis, pathway analysis and gene regulatory network inference using SCENIC.